Friday, August 01, 2008

Orthostatic intolerance

Orthostatic intolerance occurs in some humans while standing upright. This action is a fundamental stressor and requires rapid and effective circulatory and neurologic compensations to maintain blood pressure, cerebral blood flow, and consciousness. When a human stands, approximately 750 mL of thoracic blood is abruptly translocated downward. People who suffer from orthostatic intolerance - OI lack the basic mechanisms to compensate for this deficit. Changes in heart rate, blood pressure, and cerebral blood flow that produce OI "may be related to abnormalities in the interplay between blood volume control, the cardiovascular system, the autonomic nervous system and local circulatory mechanisms that regulate these basic physiological functions.

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2 Comments:

Anonymous Anonymous said...

Greg Page, also known as the Yellow Wiggle is suffering from orthostatic intolerance.

"Greg has been suffering symptoms for many months, affecting his ability to perform. The condition is related to blood pressure and while in no way life threatening it affects his balance, breathing and coordination at unpredictable times and with varying severity. Greg has discovered he is genetically predisposed to this condition and that he now needs to focus on managing his health."

12:21 AM  
Blogger Lois said...

I, too, also suffer from Orthostatic intolerance and would like to know if Greg has found any relief or research to help us along. I would appreciate any update you may have concerning this debilitating condition. Good luck Greg.......Lois of PA

8:05 PM  

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